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JoVE Journal
Neuroscience

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Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure
 

Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure

Article DOI: 10.3791/59234-v 09:34 min August 27th, 2019
August 27th, 2019

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Summary

Single-fiber recording is an effective electrophysiological technique that is applicable to the central and peripheral nervous systems. Along with the preparation of intact DRG with the attached sciatic nerve, the mechanism of conduction failure is examined. Both protocols improve the understanding of the peripheral nervous system's relationship with pain.

Tags

Keywords: Single-fiber Recording Dorsal Root Ganglion Sciatic Nerve Conduction Failure Ringer's Solution Nerve Trunk Recording Electrode Receptive Field C-fiber
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