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Surgical Approach for Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke in Mice
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Surgical Approach for Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke in Mice

Surgical Approach for Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke in Mice

DOI:
10.3791/54302-v

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10:30 min

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October 20, 2016

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,
1Department of Molecular & Cellular Physiology, Health Sciences Center Shreveport,Louisiana State University

Chapters

  • 00:05Title
  • 00:52Occlusion of the MCA
  • 03:24Reperfusion
  • 04:29Post-operative Neurological Scores and Measurement of Brain Infarct Volume
  • 07:59Results: Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke
  • 09:32Conclusion

Summary

Automatic Translation

Automatic Translation

In order to understand the pathophysiology of stroke, it is important to use reliable models. This paper will describe one of the most frequently used stroke models in mice, termed the middle cerebral artery occlusion (MCAo) model (also termed the intraluminal filament or suture model) with reperfusion.

Tags

Middle Cerebral Artery OcclusionIschemic StrokeLonga MethodMouse ModelAnesthesiaBody TemperatureCarotid Artery DissectionMonofilament InsertionReperfusionInfarct VolumeLeukocyte-endothelial Cell Interactions

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