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Switchable Acoustic and Optical Resolution Photoacoustic Microscopy for In Vivo Small-animal Blood Vasculature Imaging
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Bioengineering
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JoVE Journal Bioengineering
Switchable Acoustic and Optical Resolution Photoacoustic Microscopy for In Vivo Small-animal Blood Vasculature Imaging

Switchable Acoustic and Optical Resolution Photoacoustic Microscopy for In Vivo Small-animal Blood Vasculature Imaging

DOI:
10.3791/55810-v

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10:17 min

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June 26, 2017

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, ,
1School of Chemical and Biomedical Engineering,Nanyang Technological University

Chapters

  • 00:05Title
  • 01:00Acoustic-resolution and Optical-resolution Photoacoustic Microscopy (AR-OR-PAM) System Setup
  • 04:07AR-OR-PAM System Alignment
  • 05:36Quantification of Lateral Resolution and Imaging Depth
  • 07:23In Vivo Imaging of a Mouse Ear
  • 08:54Results: In Vivo Blood Vasculature Imaging with AR-OR-PAM
  • 09:23Conclusion

Summary

Automatic Translation

Automatic Translation

Here a switchable acoustic resolution (AR) and optical resolution (OR) photoacoustic microscopy (AR-OR-PAM) system capable of both high resolution imaging at shallow depth and low resolution deep tissue imaging on the same sample in vivo is demonstrated.

Tags

Photoacoustic MicroscopySwitchable Acoustic And Optical ResolutionIn Vivo Small-animal ImagingBlood VasculatureNd:YAG LaserDitunable LaserOptical CageAR-PAMOR-PAMUltrasonic TransducerOptical CondenserSingle-mode FiberAchromatic Doublet Lens

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