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Laser Doppler: A Tool for Measuring Pancreatic Islet Microvascular Vasomotion In Vivo
JoVE Journal
Medicine
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JoVE Journal Medicine
Laser Doppler: A Tool for Measuring Pancreatic Islet Microvascular Vasomotion In Vivo
DOI:

10:39 min

March 08, 2018

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Chapters

  • 00:04Title
  • 01:49Using Streptozotocin and Sugar-water to Make Mice Diabetic
  • 03:12Preparing and Calibrating the Laser Doppler
  • 04:24Laser Doppler Analysis of Microvascular Vasomotion in Pancreatic Islet
  • 07:56Results: Microvascular Vasomotion in the Pancreatic Islet of STZ-induced Diabetic Mice
  • 09:11Conclusion

Summary

Automatic Translation

Pancreatic islet microvascular vasomotion regulates islet blood distribution and maintains the physiological function of islet β cells. This protocol describes using a laser Doppler monitor to determine the functional status of pancreatic islet microvascular vasomotion in vivo and to assess the contributions of pancreatic islet microcirculation to pancreatic-related diseases.

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