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JoVE Journal Neuroscience
C57BL/6 小鼠自身免疫性神经炎的功能和病理评价的简易方法
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C57BL/6 小鼠自身免疫性神经炎的功能和病理评价的简易方法

Article DOI: 10.3791/56455-v • 07:30 min • November 9th, 2017
November 9th, 2017 •
1, 1, 1, 1, 1, 1
1Department of Anatomy and Neuroscience, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne

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本报告概述了一个简单的方法, 成功诱导实验性自身免疫神经炎 (一) 使用髓磷脂蛋白零 (P0)180-199肽结合弗氏的完整佐剂和百日咳毒素。我们提出了一个复杂的范例, 能够准确地评估在这一过程中出现的功能性赤字和神经病的程度。

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神经科学 问题 129 实验性自身免疫神经炎 轴突损伤 郎 周围神经 鞘 小鼠模型
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