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Chemistry

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JoVE Journal Chemistry
Aspect technique de la synthèse automatisée et de l'évaluation cinétique en temps réel de [11C]SNAP-7941
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Aspect technique de la synthèse automatisée et de l'évaluation cinétique en temps réel de [11C]SNAP-7941

Article DOI: 10.3791/59557-v • 09:50 min • April 28th, 2019
April 28th, 2019 •
1, 1, 1, 1,2, 1, 1,3, 1,4, 1
1Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, 2Department for Pharmaceutical Technology and Biopharmaceutics, Faculty of Life Sciences, University of Vienna, 3Ludwig Boltzmann Institute Applied Diagnostics, 4CBmed GmbH - Center for Biomarker Research in Medicine

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Ici, nous représentons un protocole pour la radioétiquetage entièrement automatisé de [11C]SNAP-7941 et l'analyse de la cinétique en temps réel de ce PET-tracer sur les cellules exprimantes et non-exprimantes P-gp.

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Chimie Numéro 146 radiosynthèse PET LigandTracer MCHR1 SNAP-7941 P-glycoprotéine carbone-11
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