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Journal / Neuroscience / Effektiv Gene Delivery i flera CNS territorierna…
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Neuroscience

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JoVE Journal Neuroscience
Effektiv Gene Delivery i flera CNS territorierna Använda I Utero Elektroporation
Functional Neuroimaging Using Ultrasonic Blood-brain Barrier Disruption and Manganese-enhanced MRI
Journal (Neuroscience)
Functional Neuroimaging Using Ultrasonic Blood-brain Barrier Disruption and Manganese-enhanced MRI
Inducing Cre-lox Recombination in Mouse Cerebral Cortex Through In Utero Electroporation
Journal (Neuroscience)
Inducing Cre-lox Recombination in Mouse Cerebral Cortex Through In Utero Electroporation
 
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Effektiv Gene Delivery i flera CNS territorierna Använda I Utero Elektroporation

Article DOI: 10.3791/2957 • 13:13 min
June 23rd, 2011 •
1, 2, 1, 1,2, 1, 2, 1
1Department of Biochemistry and Molecular Biology, Hotchkiss Brain Institute, Alberta Children’s Hospital Research Institute, University of Calgary, 2Department of Medical Genetics, Alberta Children’s Hospital Research Institute, Hotchkiss Brain Institute, University of Calgary

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June 23rd, 2011

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I livmodern elektroporation möjliggör snabb genen leverans i ett rumsligt och tidsmässigt-kontrollerat sätt i utvecklingsländerna centrala nervsystemet (CNS). Här beskriver vi en mycket anpassningsbar i livmodern elektroporering protokoll som kan användas för att leverera uttryck konstruktioner i flera embryonala CNS-domäner, inklusive telencephalon, diencephalon och näthinnan.

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