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嗜碱粒细胞激活测试IgE介导的药物过敏机制的调查
JoVE Journal
Immunology and Infection
This content is Free Access.
JoVE Journal Immunology and Infection
Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
DOI:

10:22 min

September 16, 2011

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Chapters

  • 00:05Title
  • 01:46Preparation of Drug Conjugates
  • 03:11Determining the Coupling Rate of Drug Conjugates
  • 04:40Basophil Activation Test (BAT) Using Drug Conjugates
  • 07:32BAT is an Effective Tool for Determining IgE-dependent Drug Hypersensitivity
  • 09:42Conclusion

Summary

Automatic Translation

嗜碱性粒细胞活化试验是一种IgE依赖的过敏检测的有力工具<em>在体外</em>。在这里,嗜碱性粒细胞活化试验的优化协议是用来研究药物过敏。一种高效的生产药物蛋白的共价结合物及其理化性质的方法是描述。

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