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Chapters
- 00:05Title
- 01:27Preparation of Herbal Extract
- 02:20Peritoneal Macrophage Isolation
- 03:18Induction of Animal Sepsis
- 04:26Representative Results
- 07:15Conclusion
Sepsis henviser til en systemisk inflammatorisk respons syndrom skyldes en mikrobiel infektion, og kan simuleres ved en kirurgisk teknik kaldet cecal ligering og punktering (CLP). Her beskriver vi en fremgangsmåde til at anvende CLP-induceret dyremodel til screening lægeurter for terapeutiske midler.
Tags
Animal ModelSepsisHerbal TherapiesEndotoxemiaBacteremiaCecal Ligation And Puncture (CLP)Perforated AppendicitisDiverticulitisMortality RatesNeedle SizeHemodynamic Cardiovascular ResponseMetabolic ResponseImmunological ResponsePathogenesisCytokinesTNFIL-1IFN-γProinflammatory MediatorsHMGB1-neutralizing
