Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Biology

This content is Open Access.

High-throughput Physical Mapping of Chromosomes using Automated in situ Hybridization
 

High-throughput Physical Mapping of Chromosomes using Automated in situ Hybridization

Article doi: 10.3791/4007
June 28th, 2012

Summary June 28th, 2012

Genome assemblies based on massively parallel DNA sequencing technologies are usually highly fragmented. The development of physical chromosome maps can potentially improve genome assemblies. Here, we demonstrate innovative approaches to chromosome preparation, fluorescent in situ hybridization, and imaging that significantly increase throughput of the physical map development.

Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
simple hit counter