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Neuroscience

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Wholemount Immunohistochemistry for Revealing Complex Brain Topography
 

Wholemount Immunohistochemistry for Revealing Complex Brain Topography

Article doi: 10.3791/4042
April 5th, 2012 Usage Statistics

Summary April 5th, 2012

Neural circuits are topographically organized into functional compartments with specific molecular profiles. Here, we provide the practical and technical steps for revealing global brain topography using a versatile wholemount immunohistochemical staining approach. We demonstrate the utility of the method using the well-understood cytoarchitecture and circuitry of cerebellum.

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