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JoVE Journal
Immunology and Infection

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Quantitative Measurement of the Immune Response and Sleep in Drosophila
 

Quantitative Measurement of the Immune Response and Sleep in Drosophila

Article DOI: 10.3791/4355
December 4th, 2012

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Summary December 4th, 2012

To understand a link between the immune response and behavior, we describe a method to measure locomotor behavior in Drosophila during bacterial infection as well as the ability of flies to mount an immune response by monitoring survival, bacterial load, and real-time activity of a key regulator of innate immunity, NFκB.

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