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Biology

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Study of the DNA Damage Checkpoint using Xenopus Egg Extracts
 

Study of the DNA Damage Checkpoint using Xenopus Egg Extracts

Article doi: 10.3791/4449
November 5th, 2012

Summary November 5th, 2012

Xenopus egg extract is a useful model system to investigate the DNA damage checkpoint. This protocol is for the preparation of Xenopus egg extracts and DNA damage checkpoint inducing reagents. These techniques are adaptable to a variety of DNA damaging approaches in the study of the DNA damage checkpoint signaling.

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