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JoVE Journal
Biology

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Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism
 
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Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism

Article DOI: 10.3791/50840 12:38 min
December 18th, 2013

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Summary December 18th, 2013

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To study the relationship between protein homeostasis, stress and aging, we monitored changes in protein folding by following protein dysfunction, protein localization in the cell and protein stability at the organismal, cellular and protein levels, using the genetically tractable metazoan Caenorhabditis elegans as a model system.

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