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Journal
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Medicine
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造型中风小鼠:在远端大脑中动脉永久性混凝
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
Please note that all translations are automatically generated.
Click here for the English version.
造型中风小鼠:在远端大脑中动脉永久性混凝
DOI:
10.3791/51729-v
•
08:14 min
•
July 31, 2014
•
Gemma Llovera*
1,2
,
Stefan Roth*
1,2
,
Nikolaus Plesnila
2
,
Roland Veltkamp
4
,
Arthur Liesz
2
1
Institute for Stroke and Dementia Research
,
University Hospital Munich
,
2
Munich Cluster for Systems Neurology (SyNergy)
,
3
Department of Neurology
,
University Heidelberg
,
4
Imperial College
,
Charing Cross Hospital
Chapters
00:05
Title
01:38
Preparations
02:32
The Distal MCAO Model
04:52
The Cylinder Test
05:45
Measuring the Infarction
06:31
Mortality, Behavioral Change, and Infarct Characterization
07:30
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
大脑中动脉闭塞(MCAO)的各种小鼠模型被广泛应用于实验性脑研究。这里,我们表明经颅永久远侧MCAO模型,产生对应于由多数人的缺血性中风的损害施加一个大小一致的皮层梗死。
Tags
Stroke
Mouse Model
Middle Cerebral Artery
Coagulation
Infarct
Permanent Occlusion
Cortex
Reproducibility
Low Mortality
Pathophysiology
Inflammation
Angiogenesis
Plasticity
Regeneration
Therapeutic Strategies
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