Here we describe a protocol for generating human induced pluripotent stem cells from peripheral blood using an episome based reprogramming strategy and histone deacetylase inhibitors.
Hubbard, J. J., Sullivan, S. K., Mills, J. A., Hayes, B. J., Torok-Storb, B. J., Ramakrishnan, A. Efficient iPS Cell Generation from Blood Using Episomes and HDAC Inhibitors. J. Vis. Exp. (92), e52009, doi:10.3791/52009 (2014).