Induction de murin inflammation intestinale par transfert adoptif de effecteur CD4<sup> +</sup> CD45RB<sup> Haute</sup> T cellules dans des souris immunodéficientes
Here, we present a protocol to induce colonic inflammation in mice by adoptive transfer of syngeneic CD4+CD45RBhigh T cells into T and B cell deficient recipients. Clinical and histopathological features mimic human inflammatory bowel diseases. This method allows the study of the initiation of colonic inflammation and progression of disease.