Фенотипирование режим для генетически модифицированных мышей используется для изучения генов, участвующих в человеческих болезней, связанных со старением
A reverse-genetics approach to understanding gene families associated with human disease is presented, using mouse as a model system, and the subsequent mouse phenotyping schedule is described. Because mice defective in a gene of interest, HtrA2, manifested Parkinsonian symptoms, the phenotyping regimen is focused on identifying neurological defects.