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Chapters
- 00:05Title
- 01:25Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Rats
- 03:25NeMO in Female Mice
- 05:13Results: Representative NeMO Effects on Mortality, Bladder Mass, and Residual Urine Volume
- 06:39Conclusion
Traditional modeling of partial bladder outlet obstruction in rodents is fraught with animal mortality. A denervation injury from dissection around the proximal urethra and bladder neck is also of major concern. We developed and evaluated a safe and reliable mid-urethral obstruction model, avoiding the shortcomings of the traditional model.
