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在女小鼠害保留神经的中期尿道梗阻（NEMO）
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JoVE Journal Medicine
Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents
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在女小鼠害保留神经的中期尿道梗阻（NEMO）

DOI:
10.3791/55288-v

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07:42 min

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April 25, 2017

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, , ,
1Developmental and Stem Cell Biology, Research Institute,The Hospital for Sick Children, 2Institute of Medical Science,University of Toronto, 3Pediatric Urology,The Hospital for Sick Children, 4Molecular Structure and Function, Research Institute,The Hospital for Sick Children

Chapters

  • 00:05Title
  • 01:25Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Rats
  • 03:25NeMO in Female Mice
  • 05:13Results: Representative NeMO Effects on Mortality, Bladder Mass, and Residual Urine Volume
  • 06:39Conclusion

Summary

Automatic Translation

Automatic Translation

在啮齿类动物中局部膀胱出口梗阻的传统的建模是充满动物死亡率。来自各地的近端尿道和膀胱颈淋巴结清扫术一去神经损伤是主要关注的也是。我们制定并评估了安全可靠的中期，尿道梗阻模型，避免了传统模式的不足。

Tags

Keywords: Nerve-sparingMid-urethral ObstructionFemale Small RodentsBladder Outlet ObstructionBladder RemodelingGene ExpressionEpigenetic ChangesBladder Obstruction RecoveryBladder DysfunctionBladder DysmorphismSurgical TechniqueAngiocatheterBlunt DissectionSilk SutureMetal Rod

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