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Journal / Neuroscience / 用四甲基铵进行实时离子电渗疗法，以量化体细胞分数和脑细胞外空间的变性…
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JoVE Journal Neuroscience
用四甲基铵进行实时离子电渗疗法，以量化体细胞分数和脑细胞外空间的变性
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用四甲基铵进行实时离子电渗疗法，以量化体细胞分数和脑细胞外空间的变性

Article DOI: 10.3791/55755-v • 10:45 min • July 24th, 2017
July 24th, 2017 •
*1, *2,3, 4, 5, 5, 2
1Department of Medicine, University of Virginia, 2Department of Cell Biology, SUNY Downstate Medical Center, 3Neural and Behavioral Science Graduate Program, SUNY Downstate Medical Center, 4Division of Neonatology, University of Virginia, 5Department of Neuroscience and Physiology, New York University School of Medicine
* These authors contributed equally

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Summary
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该方案描述了实时离子电渗疗法，一种测量活体大脑细胞外空间（ECS）物理参数的方法。释放到ECS中的惰性分子的扩散用于计算ECS体积分数和曲折度。它是研究脑ECS急性可逆变化的理想选择。

Tags

神经科学，第125期，脑，扩散，细胞外空间，实时离子电渗疗法，离子选择性微电极，曲折度，体积分数
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