Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Genetics / Promotoren fange Hei-C: Med høy oppløsning,…
JoVE Journal
Genetics

This content is Open Access.

JoVE Journal Genetics
Promotoren fange Hei-C
Generation and Purification of Chromosome Conformation Capture (3C) Library (Video) | JoVE
Journal (Genetics)
Generation and Purification of Chromosome Conformation Capture (3C) Library (Video) | JoVE
Single Molecule Analysis of Laser Localized Psoralen Adducts
Journal (Genetics)
Single Molecule Analysis of Laser Localized Psoralen Adducts
 
Click here for the English version

Promotoren fange Hei-C: Med høy oppløsning, genomet-bred profilering av arrangøren interaksjoner

Article DOI: 10.3791/57320-v • 10:16 min • June 28th, 2018
June 28th, 2018 •
*1, *1,2, 1,3, 1,4, 1,5
1Nuclear Dynamics Programme, The Babraham Institute, Babraham Research Campus, 2IJC Building, Campus ICO-Germans Trias i Pujol, Josep Carreras Leukemia Research Institute, 3Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, 4Bioinformatics Group, The Babraham Institute, Babraham Research Campus, 5Department of Biological Science, Florida State University
* These authors contributed equally

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

DNA regulatoriske elementer, for eksempel enhancers, kontrollere genuttrykk ved fysisk å kontakte målet genet arrangører, ofte gjennom langtrekkende chromosomal interaksjoner spenner genomisk distanser. Promotoren fange Hi-C (PCHi-C) identifiserer betydelig interaksjon mellom arrangører og distale regioner, aktivere tilordningen av potensielle regulatoriske sekvenser til sine mål gener.

Tags

Genetikk problemet 136 3D genomet organisasjon arrangører enhancers langtrekkende interaksjoner Hi-C cis-regulatoriske elementer genomet hele foreningen studie (GWAS) ikke-koding sykdom varianter chromatin looper CHiCAGO HiCUP
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter