A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center,Ohio State University Wexner Medical Center, 2Department of Surgery, Division of Transplant,Ohio State University Wexner Medical Center, 3Department of Surgery, Division of CardioThoracic Surgery,Ohio State University Wexner Medical Center, 4Department of Medicine,Ohio State University Wexner Medical Center
Chapters
- 00:04Title
- 00:36Preparation of the Portal Vein Cuff and Bile Duct Cannula
- 01:20Liver Procurement Procedure
- 05:24Ex Vivo Normothermic Liver Perfusion
- 06:58Results: Analysis of Tissue Damage in Base Perfusate-only and Base Perfusate and Plus PEG-CAT Groups
- 07:56Conclusion
Det saknas betydande lever givare och kriterier för levern har utökats. Normothermic ex vivo lever perfusion (NEVLP) har utvecklats för att utvärdera och ändra organfunktion. Denna studie visar en råtta modell av NEVLP och tester pegylerat-katalas, förmåga att minska levern bevarande skada.
