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JoVE Journal
Biology

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Novel Method of Plasmid DNA Delivery to Mouse Bladder Urothelium by Electroporation
 

Novel Method of Plasmid DNA Delivery to Mouse Bladder Urothelium by Electroporation

Article DOI: 10.3791/57649
May 3rd, 2018

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Summary May 3rd, 2018

We describe a novel method for the delivery of DNA plasmid into the urothelial cells of mouse bladder in vivo through urethra catheterization and electroporation. It offers a fast and convenient way for generating autochthonous mouse models of bladder diseases.

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