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Chapters
- 00:04Title
- 00:55Mouse Mesenteric Artery Dissection
- 02:26Arterial Mounting
- 05:30Normalization
- 07:03Artery Contraction Recording
- 08:18Results: Representative Tracings Showing the Normalization Procedure, Potentiation by High-K+ Solution, and Contraction
- 08:47Conclusion
La técnica del miógrafo de alambre se utiliza para investigar las funciones del músculo liso vascular y nuevos fármacos de la pantalla. Se presenta un protocolo detallado para medir la contractilidad isométrica de la arteria mesentérica de ratón y para la detección de nuevos relajantes del músculo liso vascular.
Tags
Isometric ContractilityWire MyographyMesenteric ArteryVascular Smooth MuscleContractility MeasurementHypertension TherapyHigh PotassiumMulti-channel SystemDrug ScreeningEuthanized MouseGastrointestinal TractMesenteric Artery DissectionHEPES-Tyrode SolutionStereoscopic MicroscopeCalcium-free SolutionArtery SegmentStainless Steel Wire
