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Immunology and Infection
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干细胞衍生病毒Ag特异性T淋巴细胞抑制小鼠HBV复制
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Immunology and Infection
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JoVE Journal
Immunology and Infection
Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Please note that all translations are automatically generated.
Click here for the English version.
干细胞衍生病毒Ag特异性T淋巴细胞抑制小鼠HBV复制
DOI:
10.3791/60043-v
•
07:25 min
•
September 25, 2019
•
Xiaofang Xiong
,
Fengyang Lei
,
Mohammad Haque
,
Jianxun Song
1
Department of Microbial Pathogenesis and Immunology
,
Texas A&M University Health Science Center
,
2
Department of Ophthalmology
,
Harvard Medical School
Chapters
00:04
Title
00:34
Antigen (Ag)‐ Specific CD8+ T cell Generation
02:01
Hydrodynamic Herpes B Virus (HBV) Plasmid Delivery for HBV Replication Induction
02:43
HBV Replication Reduction
03:38
HBV Replication Reduction Analysis
05:30
Results: Representative Effects of Stem Cell-Derived Viral Ag-Specific T Lymphocyte HBV Replication Suppression
06:58
Conclusion
Summary
Automatic Translation
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这里介绍了一个协议,通过利用干细胞衍生病毒抗原(Ag)特异性T淋巴细胞的采用细胞转移(ACT),有效抑制小鼠乙型肝炎病毒(HBV)复制。这个程序可以适应潜在的基于ACT的HBV感染免疫治疗。
Tags
Stem Cell
Viral Antigen-specific T Lymphocytes
HBV Replication
IPSC-derived T Cells
Adoptive Cell Transfer
T Cell Receptor
HBV Plasmid
Hydrodynamic Delivery
CD8-positive T Cells
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