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Stem Cell-avledet viral AG-spesifikke T-lymfocytter Undertrykk HBV-replikering i mus
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
DOI:

07:25 min

September 25, 2019

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Chapters

  • 00:04Title
  • 00:34Antigen (Ag)‐ Specific CD8+ T cell Generation
  • 02:01Hydrodynamic Herpes B Virus (HBV) Plasmid Delivery for HBV Replication Induction
  • 02:43HBV Replication Reduction
  • 03:38HBV Replication Reduction Analysis
  • 05:30Results: Representative Effects of Stem Cell-Derived Viral Ag-Specific T Lymphocyte HBV Replication Suppression
  • 06:58Conclusion

Summary

Automatic Translation

Presentert her er en protokoll for effektiv undertrykkelse av hepatitt B-viruset (HBV) replikering i mus ved å utnytte adoptiv celle overføring (ACT) av stilk cellen-avledet viral antigen (AG)-spesifikke T-lymfocytter. Denne prosedyren kan tilpasses for potensielle ACT-baserte immunterapi av HBV-smitte.

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