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Een Ex Vivo Choroid Sprouting Assay van Oculaire Microvasculaire Angiogenese
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Een Ex Vivo Choroid Sprouting Assay van Oculaire Microvasculaire Angiogenese

Article DOI: 10.3791/61677-v • 06:10 min • August 6th, 2020
August 6th, 2020 •
1, 2, 1, 1, 1,3, 1
1Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, 2Department of Clinical and Metabolic Genetics, Hospital for Sick Children, University of Toronto, 3Manton Center for Orphan Disease, Harvard Medical School, Boston Children's Hospital

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Dit protocol presenteert choroïde kiemen test, een ex vivo model van microvasculaire proliferatie. Deze test kan worden gebruikt om trajecten die betrokken zijn bij het verspreiden van choroidale microvaten te beoordelen en te beoordelen drug behandelingen met behulp van wilde type en genetisch gemodificeerd muisweefsel.

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Biologie choroïde ontkiemende test endotheelcellen netvliespigment epitheel RPE choroidale angiogenese choroidale neovascularisatie leeftijdsgebonden maculadegeneratie AMD ex vivo
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