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Valutazione delle proprietà angiogenetiche delle cellule staminali del cancro ovarico utilizzando il sistema di co-coltura tridimensionale, NICO-1
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Valutazione delle proprietà angiogenetiche delle cellule staminali del cancro ovarico utilizzando il sistema di co-coltura tridimensionale, NICO-1

Article DOI: 10.3791/61751-v • 07:59 min • December 5th, 2020
December 5th, 2020 •
1, 1, 2,3, 2,3, 2, 1, 1, 1, 1, 1, 1, 1, 3, 2, 1
1Department of Obstetrics and Gynecology, Teikyo University School of Medicine, 2Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, 3Devision of Cancer Differentiation, National Cancer Center Research Institute

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Le cellule staminali del cancro ovarico (OCSC) sono responsabili dell'inizio del cancro, della recidiva, della resistenza terapeutica e delle metastasi. Si ritiene che la nicchia vascolare OCSC promuova l'autorinnovamento degli OCSC, portando alla chemioresistenza. Questo protocollo fornisce la base per stabilire un modello di nicchia vascolare OCSC riproducibile in vitro.

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Biologia Numero 166 cancro ovarico ascite cellule staminali tumorali nicchia vascolare co-coltura angiogenesi
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