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Journal / Bioengineering / Microscopia Multifotol Intravital em Tempo Real…
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Bioengineering
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JoVE Journal Bioengineering
Microscopia Multifotol Intravital em Tempo Real para visualizar tratamentos focados de ultrassom e microbolhas para aumentar a permeabilidade da barreira hematoencefálica
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Microscopia Multifotol Intravital em Tempo Real para visualizar tratamentos focados de ultrassom e microbolhas para aumentar a permeabilidade da barreira hematoencefálica

Article DOI: 10.3791/62235-v • 06:29 min • February 5th, 2022
February 5th, 2022 •
1,2, *3, *3, 4,5, 3, 1,2,6
1Physical Sciences Platform, Sunnybrook Research Institute, 2Institute of Biomedical Engineering, University of Toronto, 3Department of Physics, Norwegian University of Science and Technology, 4Department of Clinical Medicine, University of Bergen, 5Exact Therapeutics AS, 6Department of Medical Biophysics, University of Toronto
* These authors contributed equally

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Este protocolo descreve os procedimentos cirúrgicos e técnicos que permitem imagens de fluorescência multifotona em tempo real do cérebro de roedores durante tratamentos de ultrassom e microbolhas focados para aumentar a permeabilidade da barreira hematoencefálica.

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Bioengenharia Edição 180 ultrassom focado microscopia multifotônica microscopia intravital barreira hemencefálica microbolhas ultrassom terapêutico
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