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Implantation of Ferumoxides Labeled Human Mesenchymal Stem Cells in Cartilage Defects
JoVE Journal
Biology
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JoVE Journal Biology
Implantation of Ferumoxides Labeled Human Mesenchymal Stem Cells in Cartilage Defects
DOI:

04:39 min

April 05, 2010

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Chapters

  • 00:00Title
  • 00:33Introduction
  • 01:14Labeling of hMSCs with Endorem
  • 02:24Creating Matrix Associated Stem Cell Implants (MASI)
  • 03:28Representative Labeling and Implantation Results
  • 03:57Conclusion

Summary

Automatic Translation

Goal of the presentation is to demonstrate a highly reproducible method to generate matrix associated stem cell implants in cartilage defects, which can be visualized with MR imaging. Stem cells are labeled with FDA-approved Ferumoxides, mixed with agarose, implanted into cartilage defects and imaged with a 7T MR scanner.

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