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Journal
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Neuroscience
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调查轻度创伤性脑损伤海马电路功能的改变
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Please note that all translations are automatically generated.
Click here for the English version.
调查轻度创伤性脑损伤海马电路功能的改变
DOI:
10.3791/4411-v
•
10:59 min
•
November 19, 2012
•
Colin J. Smith
2
,
Brian N. Johnson
,
Jaclynn A. Elkind
,
Jill M. See
,
Guoxiang Xiong
,
Akiva S. Cohen
3
1
Division of Neurology
,
Children’s Hospital of Philadelphia
,
2
Neuroscience Graduate Group
,
Perelman School of Medicine at the University of Pennsylvania
,
3
Department of Pediatrics
,
Perelman School of Medicine at the University of Pennsylvania
Chapters
00:05
Title
02:08
Lateral Fluid Percussion Injury
03:04
Behavioral Analysis- Conditioned Fear Response
03:42
Acute Hippocampal Slice Preparation
04:41
Extracellular Field Potential Recording and Visualized Patch-clamp Recording
06:43
Voltage Sensitive Dye Imaging
08:39
Results: Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
10:33
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
一个多层面的方式来调查海马电路的功能变化进行了解释。电技术,以及受伤的协议,行为检测和区域的清扫方法。可以应用这些技术的组合,以类似的方式用于其他大脑区域和科学问题。
Tags
Investigations
Alterations
Hippocampal Circuit Function
Mild Traumatic Brain Injury
TBI
Neurological Impairments
Memory Deficits
Seizure Threshold
Hippocampal Dysfunction
Lateral Fluid Percussion Injury
Animal Model
Neuronal Cell Loss
Gliosis
Ionic Perturbation
Combinatorial Method
Ex Vivo Physiological Techniques
Animal Behavior Analysis
Biochemical Analysis
Cognitive Disability
Extracellular Field Potential Recording
Whole-cell Patch-clamping
Voltage Sensitive Dye Recording
Regionally Dissecting Subregions Of The Hippocampus
Neurochemical Analysis
Metabolic Analysis
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