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Cel dood in verband met abnormale Mitosis Waargenomen door confocale Imaging Live kankercellen
 

Cel dood in verband met abnormale Mitosis Waargenomen door confocale Imaging Live kankercellen

Article doi: 10.3791/50568
August 21st, 2013

Summary August 21st, 2013

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De cytotoxische activiteit van de fenanthridine PJ-34 in kankercellen ondergaan mitose werd in real time gedocumenteerd door levende confocale beeldvorming. PJ-34 uitgeroeide menselijke borstkanker MDA-MB-231 cellen die extra-centrosomes in mitose. In tegenstelling tot normale bifocale mitose, werden de extra-centrosomes niet geclusterd in de twee polen spil in aanwezigheid van PJ-34.

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