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JoVE Journal
Biology

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Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions
 

Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions

Article DOI: 10.3791/51872
August 2nd, 2015

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Summary August 2nd, 2015

Using protein microarrays containing nearly the entire S. cerevisiae proteome is probed for rapid unbiased interrogation of thousands of protein-protein interactions in parallel. This method can be utilized for protein-small molecule, posttranslational modification, and other assays in high-throughput.

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