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Intravenøse injektioner i neonatale mus
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JoVE Journal Biology
Intravenous Injections in Neonatal Mice

Intravenøse injektioner i neonatale mus

DOI:
10.3791/52037-v

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05:17 min

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November 11, 2014

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, ,
1Department of Neuroscience,Ohio State University, 2Center for Gene Therapy, Nationwide Children’s Hospital Research Institute,Ohio State University

Chapters

  • 00:05Title
  • 00:52Preparation and Injection Procedure
  • 03:06Post-Injection
  • 04:04Results: GFP Expression after Neonate Intravenous Injection
  • 04:55Conclusion

Summary

Automatic Translation

Automatic Translation

Dyremodeller for pædiatrisk sygdom kan opleve tidlig debut og aggressiv sygdomsprogression. Klinisk relevant levering terapi til unge musemodeller kan være teknisk vanskeligt. Denne protokol beskriver en ikke-invasiv intravenøs injektion metode til nyfødte mus inden for de første to postnatal levedage.

Tags

Intravenous InjectionNeonatal MiceTemporal VeinAdeno-associated VirusAAVTransgene ExpressionTherapeutic DeliveryMouse ModelsEarly Onset Disease

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