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JoVE Journal
Neuroscience

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JoVE Journal Neuroscience
The Neuromuscular Junction
 

The Neuromuscular Junction: Measuring Synapse Size, Fragmentation and Changes in Synaptic Protein Density Using Confocal Fluorescence Microscopy

Article doi: 10.3791/52220
December 26th, 2014 • Usage Statistics
1, 2, 1, 3, 1, 1, 1
1Physiology and Bosch Institute, University of Sydney, 2Motor Neuron Disease Research Group, Australian School of Advanced Medicine, Macquarie University, 3Advanced Microscopy Facility, Bosch Institute, University of Sydney

Summary
Automatic Translation
December 26th, 2014

The neuromuscular junction (NMJ) is altered in a variety of conditions that can sometimes culminate in synaptic failure. This report describes fluorescence microscope-based methods to quantify such structural changes.

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