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Biology

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A Cell Free Assay to Study Chromatin Decondensation at the End of Mitosis
 

A Cell Free Assay to Study Chromatin Decondensation at the End of Mitosis

Article DOI: 10.3791/53407
December 19th, 2015

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Summary December 19th, 2015

The molecular mechanisms of the decondensation of highly compacted mitotic chromatin are ill-defined. We present a cell-free assay based on mitotic chromatin clusters isolated from HeLa cells and Xenopus laevis egg extract that faithfully reconstitutes the decondensation process in vitro.

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