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JoVE Journal
Neuroscience

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Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons
 

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons

Article DOI: 10.3791/53818
March 28th, 2016

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Summary March 28th, 2016

Here, a procedure to selectively activate a neuronal protein with a short pulse of light by genetically encoding a photo-reactive unnatural amino acid into a target neuronal protein expressed in neurons in culture or in vivo is presented.

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