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Cefoperazone behandlet musemodell for klinisk relevante<em> Clostridium difficile</em> Strain R20291
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
DOI:

06:51 min

December 10, 2016

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Chapters

  • 00:05Title
  • 00:53Inoculation of Mice with Clostridium difficile
  • 03:22Enumeration of C. difficile from Mouse Fecal Content
  • 05:03Results: The Murine Model of C. difficile Infection Demonstrates Significant Weight Loss, Bacterial Colonization and Histopathological Changes in Infected Mice
  • 06:10Conclusion

Summary

Automatic Translation

Denne protokollen beskriver cefoperazone musemodell for Clostridium difficile infeksjon (CDI) med en klinisk relevant og genetisk medgjørlig stamme, R20291. Vekt på klinisk sykdom overvåking, C. difficile bakteriell telling, toksin cytotoksisitet, og histopatologiske endringer gjennom CDI i en musemodell er beskrevet i protokollen.

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