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The ChIP-exo Method
 

The ChIP-exo Method: Identifying Protein-DNA Interactions with Near Base Pair Precision

Article doi: 10.3791/55016
December 23rd, 2016

Summary December 23rd, 2016

Here, we present a protocol to achieve near base pair resolution of protein-DNA interactions. This is obtained by exonuclease treatment of DNA fragments selectively enriched by chromatin immunoprecipitation (ChIP-exo) followed by high throughput sequencing.

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