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JoVE Journal
Cancer Research

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基于免疫荧光显微镜的瞬时和持久双链 dna 损伤 dna 修复过程的表征
 
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基于免疫荧光显微镜的瞬时和持久双链 dna 损伤 dna 修复过程的表征

Article DOI: 10.3791/57653
June 8th, 2018

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Summary June 8th, 2018

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双链 DNA 断裂的修复是一个动态过程, 不仅需要在断裂时形成修复配合物, 而且要解决病变后的解决方法。在这里, 我们使用免疫荧光显微镜的短暂和长期的双滞留断裂作为一个工具来解剖这个基因组维持机制。

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