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JoVE Journal
Biology

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A Proximal Culture Method to Study Paracrine Signaling Between Cells
 

A Proximal Culture Method to Study Paracrine Signaling Between Cells

Article doi: 10.3791/58144
August 28th, 2018

Summary August 28th, 2018

Paracrine and juxtacrine cellular interactions play an important role in many biological processes, including tumor progression, immune responses, angiogenesis, and development. Here, a proximal culture method is used to study paracrine signaling where the localized concentrations of the secreted factors are maintained while preventing direct cellular contact.

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