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Generering af heterogene stof gradienter på tværs af Cancer populationer på en Microfluidic Evolution Accelerator for real-time observation
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Generation of Heterogeneous Drug Gradients Across Cancer Populations on a Microfluidic Evolution Accelerator for Real-Time Observation
DOI:

10:24 min

September 19, 2019

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Chapters

  • 00:04Title
  • 01:09Fabrication of Metal Plate Holder and Cell Line Seeding
  • 03:05Setting up Thermal Control Unit and Gas Supply System
  • 03:50Installation of Microfluidic Device
  • 08:12Results: Growth Curves and Cell Motility Assay
  • 09:33Conclusion

Summary

Automatic Translation

Vi præsenterer en mikrofluidisk Cancer-on-chip model, "Evolution Accelerator" teknologi, som giver en kontrollerbar platform for langsigtede real-time kvantitative undersøgelser af Cancer dynamik inden for veldefinerede miljømæssige forhold på enkelt-celle Niveau. Denne teknologi forventes at fungere som en in vitro-model for grundforskning eller præklinisk lægemiddeludvikling.

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