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JoVE Journal Medicine
Un modelo murino de exposición fetal a la inflamación materna para estudiar los efectos de la coleamnionitis aguda en el desarrollo intestinal neonatal
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Un modelo murino de exposición fetal a la inflamación materna para estudiar los efectos de la coleamnionitis aguda en el desarrollo intestinal neonatal

Article DOI: 10.3791/61464-v • 08:50 min • June 24th, 2020
June 24th, 2020 •
1, 1, 2, 1, 3, 1,4
1Division of Neonatology, Stead Family Department of Pediatrics, University of Iowa, 2Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, University of Iowa, 3Division of Neonatology, Department of Pediatrics, Vanderbilt University, 4Department of Microbiology & Immunology, University of Iowa

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Desarrollamos un modelo de coleamnionitis para simular la exposición fetal a la inflamación materna (FEMI) sin complicaciones de organismos vivos para examinar los efectos del FEMI en el desarrollo del tracto intestinal de la descendencia. Esto permite el estudio de causas mecanicistas para el desarrollo de lesiones intestinales después de la coleamnionitis.

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Este mes en JoVE Número 160 Lipopolisacáridos (LPS) Exposición fetal a la inflamación materna (FEMI) Chorioamnionitis Desarrollo Intestinal Célula de Paneth Célula de Copa
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