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高通量化学化合物筛选，以阐明其对细菌持久性的影响
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Immunology and Infection
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JoVE Journal Immunology and Infection
High-throughput Screening of Chemical Compounds to Elucidate Their Effects on Bacterial Persistence
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高通量化学化合物筛选，以阐明其对细菌持久性的影响

DOI:
10.3791/61597-v

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07:25 min

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February 23, 2021

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,
1Department of Chemical and Biomolecular Engineering,University of Houston

Chapters

  • 00:05Introduction
  • 00:33Microarray Plate Screening
  • 03:26Validating the Identified Conditions
  • 05:30Results: Microarray and Validation
  • 06:36Conclusion

Summary

Automatic Translation

Automatic Translation

在本方法论文中，我们提出了一种高通量筛选策略，以识别对细菌持久性有重大影响的化合物，如渗透物。

Tags

High-throughput ScreeningBacterial PersistenceChemical CompoundsDrug PanelsGene LibrariesMicroarrayOfloxacinPersister AssayColony Forming Units (CFUs)Serial DilutionOrbital ShakerModified LB Medium

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