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JoVE Journal
Immunology and Infection

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A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules
 

A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

Article DOI: 10.3791/55199
March 10th, 2017

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Summary March 10th, 2017

We present in the current study a novel fluorescence-based assay using lymphocytes derived from a transgenic mouse. This assay is suitable for high-throughput screening (HTS) of small molecules endowed with the capacity of either inhibiting or promoting lymphocyte activation.

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