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一个串行收集脑脊液从池鼠标麦格纳技术
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Biology
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JoVE Journal
Biology
A Technique for Serial Collection of Cerebrospinal Fluid from the Cisterna Magna in Mouse
Please note that all translations are automatically generated.
Click here for the English version.
一个串行收集脑脊液从池鼠标麦格纳技术
DOI:
10.3791/960-v
•
08:08 min
•
November 10, 2008
•
Li Liu
,
Karen Duff
1
Department of Pathology
,
Columbia University
Chapters
00:00
Title
01:02
Introduction
02:10
Making the Glass Capillary
02:52
Anesthetizing the Mice
03:19
Preparing the Mouse for CSF Sampling
04:42
Collecting CSF Using the Cisterna Magna Puncture Technique
06:03
After CSF Sampling
06:51
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
转基因(TG)AD小鼠模型提供了一个极好的机会,探讨如何以及为什么脑脊液中的Aβ或tau蛋白水平变化的疾病在人类患者进展。在这里,我们展示了一个串行鼠标脑脊液采样精枕大池穿刺技术。
Tags
Cerebrospinal Fluid
CSF
Cisterna Magna
Mouse
Alzheimer’s Disease
AD
Neurodegenerative Disease
Amyloid Peptide
Tau Protein
Biochemical Changes
Transgenic Mouse Models
Puncture Technique
Sampling
Aβ42
Tau Levels
Disease Progression
ELISA
Metabolism
Article
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