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A Technique for Serial Collection of Cerebrospinal Fluid from the Cisterna Magna in Mouse
JoVE Journal
Biology
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JoVE Journal Biology
A Technique for Serial Collection of Cerebrospinal Fluid from the Cisterna Magna in Mouse

A Technique for Serial Collection of Cerebrospinal Fluid from the Cisterna Magna in Mouse

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08:08 min

November 10, 2008

DOI:

08:08 min
November 10, 2008

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Summary

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Transgenic (Tg) mouse models of AD provide an excellent opportunity to investigate how and why Aβ or tau levels in CSF change as the disease progresses in human patients. Here, we demonstrate a refined cisterna magna puncture technique for serial CSF sampling from the mouse.

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