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Intraductal Injektion af LPS som en musemodel af Mastitis
 
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Intraductal Injektion af LPS som en musemodel af Mastitis: Signaling visualiseres via en NF-KB Reporter Transgenic

Article DOI: 10.3791/4030-v 08:51 min September 4th, 2012
September 4th, 2012

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Summary

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Beskrevet her er en teknik, hvor lipopolysaccharid injiceres i lakterende muse brystkirtel via brystvorten at simulere mastitis, en betingelse, der almindeligvis forårsaget af bakteriel infektion. Lipopolysaccharid injektion resulterer i øget nuclear factor kappa B (NF-KB) signalering, visualiseret ved bioluminescerende billeddannelse af en NF-KB luciferase reporter mus.

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Medicin mastitis intraductal injektion NF-kappaB reporter transgene LPS bioluminescerende billeddannelse laktation
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