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Endothelin-1 Induced Middle Cerebral Artery Occlusion Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Rat
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Endothelin-1 Induced Middle Cerebral Artery Occlusion Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Rat

Endothelin-1 Induced Middle Cerebral Artery Occlusion Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Rat

DOI:
10.3791/50014-v

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07:26 min

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February 16, 2013

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, , , , , , ,
1Department of Neurosurgery,University of Florida , 2Department of Anatomical Sciences,Shiraz University of Medical Sciences, Shiraz, Iran , 3Department of Physiology and Functional Genomics,University of Florida , 4Department of Neurology,University of Florida

Chapters

  • 00:01Title
  • 00:22Introduction
  • 05:10Representative Results
  • 05:53Conclusion

Summary

Automatic Translation

Automatic Translation

Several animal models of cerebral ischemia have been developed to simulate the human condition of stroke. This protocol describes the endothelin-1 (ET-1) induced middle cerebral artery occlusion (MCAO) model for ischemic stroke in rats. In addition, important considerations, advantages, and shortcomings of this model are discussed.

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Endothelin-1Middle Cerebral Artery OcclusionIschemic StrokeLaser Doppler FlowmetryRat Model

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